AlCl₃‐Promoted Conia‐Ene‐Related Cyclization of α,ω‐Diethylenic Ketones and 1,2‐ or 1,3‐Hydroalkenylation of Unactivated Cyclopropanes

Abstract α,β‐Unsaturated enones possessing an unactivated olefin at the ϵ‐, ζ‐ or η‐position underwent aluminum chloride‐promoted Conia‐ene‐related cyclization, affording unsaturated decalones hexahydroindenones in generally good yields. Cyclopropanes could be used as surrogates this process, leading to same bicyclic products slightly improved efficiency result of 1,2‐ 1,3‐hydroalkenylation reactions. This method provided access a whole range bi‐ tricyclic enone synthons, some which were potentially useful odorants synthesis biologically active molecules.